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Horror games about human experiments on PlayStation

In these games someone has been testing on people: a company lab under a mansion, a father's basement, a classified study you signed up for, a facility that keeps its captives as specimens. You are often the test subject yourself, or you walk through what the tests left behind. The fear is in the cells, the records and the people who are still running the work.

The top 30 of 40 horror games about human experiments on PlayStation, ranked by player and critic scores

The 30 best on PlayStation

  1. Resident Evil Requiem art: Grace Ashcroft, with pale, tousled hair and a brown leather jacket, looks sideways on a grey city street SurvivalResident Evil RequiemA blind girl, Emily, is held captive and experimented on, and the villain is a former Umbrella scientist. 96% on Steam (187,672 reviews)12 h or morePaidPC, PlayStation, Xbox, Switch
  2. INSIDE key art: the boy hides behind a pillar in a dark factory while a machine sweeps the room with a searchlight PsychologicalINSIDEDeeper in, a facility of scientists runs experiments on bodies kept under water. 97% on Steam (76,338 reviews)about 2 hPaidPC, PlayStation, Xbox, Switch, iPhone
  3. Outlast library art: a hulking scarred inmate with a stitched grin and glowing eyes stands in a dark asylum corridor, seen in green night vision SurvivalOutlastMurkoff's secret "research and charity" branch runs the asylum, and the store calls it hell as an experiment you can't survive. 93% on the PlayStation Store (179,484 ratings)about 5 hPaidPC, Mac, Linux, PlayStation, Xbox, Switch
  4. In Sound Mind key art: a man in a hat with a gaping mouth of teeth for a face, a cracked mannequin woman with a cat on her shoulder, a ghostly girl and a lighthouse PsychologicalIn Sound MindThe patients you find were all exposed to the same experimental chemical. 95% on Steam (7,056 reviews)10 h or morePaidPC, PlayStation, Xbox, Switch
  5. Dino Crisis key art: a scaly raptor foot with a raised curved sickle claw on a blood-smeared floor, lit against darkness SurvivalDino CrisisA scientist reported dead three years earlier has secretly resumed his Third Energy experiments on the island. 94% on the PlayStation Store (8,128 ratings)about 6.5 hPaidPC, PlayStation
  6. STASIS: BONE TOTEM key art: a frightened woman in a diving helmet underwater, a toothed orange-lit tentacle coiled around her in the green dark EscapeSTASIS: BONE TOTEMThe lab's experiments and twitching horrors are what the couple uncover as they explore. 93% on Steam (2,689 reviews)12 h or morePaidPC, Mac, PlayStation, Xbox, Switch
  7. Resident Evil art: the dim grand hall of the mansion with carved balconies, columns, candelabras and a central staircase SurvivalResident EvilBeneath the grounds lies a secret Umbrella laboratory where experiments were carried out. 92% on Steam (37,103 reviews)11 h or morePaidPC, PlayStation, Xbox, Switch
  8. The Outlast Trials art: three test subjects with night-vision goggles strapped to their faces, one screaming with an arm raised, in a murky olive tint SurvivalThe Outlast TrialsMurkoff conditions its test subjects, called Reagents, for obedience and to turn them into sleeper agents 92% on Steam (120,983 reviews)13 h or morePaidPC, PlayStation, Xbox
  9. Flesh Made Fear key art: a red-tinted face in a surgical mask beside a rotting skull and monsters SurvivalFlesh Made FearA former CIA scientist carries on illegal human and mind-control experiments. 93% on Steam (447 reviews)about 6 hPaidPC, PlayStation
  10. Prey key art: Morgan Yu in a red suit and glowing helmet stands beneath a huge black, smoke-like alien shape that holds the Moon and the Talos I station SurvivalPreyMorgan Yu was the key subject of an experiment meant to change humanity, run aboard the station. 91% on Steam (54,912 reviews)16 h or morePaidPC, PlayStation, Xbox
  11. Clea key art: two frightened red-haired children huddle together under a stormy night sky as pale, red-clawed hands reach for them SurvivalCleaMum and Dad have been experimenting on the Chaos Servants, and that is how the monsters got loose 97% on Steam (372 reviews)about 4.5 hPaidPC, Mac, Linux, Switch, PlayStation, Xbox
  12. Caput Mortum key art: a man in a white shirt shields his eyes and holds a dagger, ringed by green serpents and winged insects before an alchemical symbol SurvivalCaput MortumThe store warns of experiments on humans; the alchemists tried to make artificial beings. 95% on Steam (379 reviews)about 2.5 hPaidPC, PlayStation, Xbox, Switch
  13. Tormented Souls key art: a twisted figure stands in a red-lit corridor lined with suits of armour, glowing light behind it SurvivalTormented SoulsThe maker's bestiary says elderly patients were subjected to awful experiments and had their eyes replaced by tuning forks. 90% on Steam (8,283 reviews)12 h or morePaidPC, PlayStation, Xbox, Switch
  14. KARMA: The Dark World key art: monochrome portrait of a wet-haired young man in a padded suit with a thick collar and numbered chest plate, lit from above on black PsychologicalKARMA: The Dark WorldYou uncover hints of experiments Leviathan ran on its suspect, and possibly on Daniel, with serious cognitive consequences 91% on Steam (4,617 reviews)about 6 hPaidPC, PlayStation, Xbox
  15. Heaven Dust key art: a spiky-haired boy aims a handgun in front of pale zombies and a hulking mutant with an eye in its chest, beside faded top-down views of mansion rooms SurvivalHeaven DustThe company StarDust carried out research on a virus it hoped would bring immortality, and the mansion is what is left. 92% on Steam (601 reviews)about 4 hPaidPC, Switch, Xbox, PlayStation
  16. I Have No Mouth, and I Must Scream key art: a man's face with a red eye and no mouth, merged into a microchip, beside the chrome title on blue circuitry PsychologicalI Have No Mouth, and I Must ScreamNimdok's chapter is set in a Nazi concentration camp where doctors conduct medical experiments 89% on Steam (4,102 reviews)about 6 hPaidPC, Mac, Linux, PlayStation, Xbox, Switch, iPhone, Android
  17. CANINE key art: a snarling dog's face seen from below, with bared white fangs and glowing amber eyes against black SurvivalCANINEAn evil corporation kidnaps pets and runs experiments on them 96% on Steam (317 reviews)about 30 minPaidPC, Mac, Switch, PlayStation, Xbox
  18. Murky Divers key art: a diver with a three-lamp helmet reaches for a glowing severed foot in a green flooded facility, with a diver pushing a shopping cart and a ghoul behind Co-opMurky DiversYou are erasing the evidence of a drug company's failed experiments, and the creatures in the wrecks are waiting to kill you. 87% on Steam (5,339 reviews)about 3 hPaidPC, PlayStation, Xbox
  19. EMPTY SHELL key art: a figure in a gas mask dissolving into black ink splatters on a white, glitched background SurvivalEMPTY SHELLLogs from the 1950s lead toward the accident at the facility; The Games Machine calls it the classic experiment where everything went wrong 88% on Steam (723 reviews)about 4 hPaidPC, Switch, PlayStation, Xbox
  20. Stories Untold key art: a glowing red orb among old CRT monitors, a camcorder, a keypad panel and framed photos, with GET OUT on one screen PsychologicalStories UntoldIn The Lab Conduct you follow a manual to run a series of experiments, with a camera, a drill and X-ray gear, on what looks like a human heart. 87% on Steam (5,561 reviews)about 2.5 hPaidPC, Mac, PlayStation, Xbox, Switch
  21. Amanda the Adventurer 3 key art: a glowing old TV between a screaming opossum, a grumpy Wooly the sheep and a smiling Amanda, with a clawed hand reaching over it in the dark Puzzle horrorAmanda the Adventurer 3Monitors in the facility show a containment log and integrity readouts of samples taken from people. 87% on Steam (761 reviews)about 2.5 hPaidPC, PlayStation, Xbox, Switch
  22. Dying Light: The Beast key art: Kyle Crane raises a serrated blade and a flashlight against a huge infected in a flooded forest, hands reaching from the water around him Co-opDying Light: The BeastCrane escapes years of brutal experimentation in the Baron's laboratory, left with human and zombie DNA (official site). 86% on Steam (73,481 reviews)20 h or morePaidPC, PlayStation, Xbox
  23. Get Out key art: a hooded figure in a straitjacket sits cross-legged in a blue-lit prison cell, a silhouette at the barred window behind SurvivalGet Out ! A "Very Bad Dreams" StoryThe store says the creatures in the corridors are the result of experiments in the asylum that went terribly wrong. 83% on the PlayStation Store (176 ratings)about 2.5 hPaidPC, PlayStation, VR
  24. Zero Time Dilemma key art: the illustrated cast of nine, among them a figure in a round rusty helmet, stands before a riveted round hatch AnimeZero Escape: Zero Time DilemmaThe store opens with the line that the experiment wasn't supposed to be like this; the captives were part of one 81% on Steam (2,749 reviews)21 h or morePaidPC, PlayStation, Xbox
  25. Fobia - St. Dinfna Hotel key art: a figure in a dark gas mask with one green lens stands in a red-lit hotel corridor SurvivalFobia - St. Dinfna HotelThe creatures in the halls were left behind by the cult's human experiments. 83% on Steam (2,392 reviews)11 h or morePaidPC, PlayStation, Xbox
  26. Sker Ritual key art: a masked man in a bowler hat leads monsters, among them a brass-helmeted diver, out of red smoke under a fiery bird emblem Co-opSker RitualThe Quiet Ones are failed experiments that turned ravenous, now hunting you across the island. 81% on Steam (6,020 reviews)about 2 hPaidPC, PlayStation, Xbox
  27. STASIS key art: a bald man in a dark segmented suit sits hunched with a hand on his head, cables trailing from his back, in a dim industrial room lit by a purple glow 2D horrorSTASISThe Groomlake turns out to be a medical frigate used for illegal research on unwilling people. 79% on Steam (1,716 reviews)about 7 hPaidPC, Mac, PlayStation, Xbox, Switch
  28. Killing Floor 2 key art: a mercenary fights a clawed Zed as a screaming Siren, a chainsaw-armed Scrake and a glowing red Fleshpound charge through the fog Co-opKilling Floor 2The Zeds are failed clones from a Horzine Biotech experiment that escaped across Europe. 88% on Steamabout 55 minPaidPC, PlayStation, Xbox
  29. Angel Engine key art: the title beside a pale skull-like face and a bloodied figure strapped into a metal frame under robotic syringe arms Night shiftAngel EngineYour job is to correct deformities on test subjects at the Babel 2 Scientific Research Center. 79% on Steam (309 reviews)about 2.5 hPaidPC, PlayStation, Xbox, Switch
  30. Rise of Insanity key art: a sepia creature whose head is a cluster of screaming faces, a bird skull and animal heads, in a dim vaulted room PsychologicalRise of InsanityDowell tests his experimental treatment methods on a new patient with contradictory symptoms. 79% on Steam (961 reviews)about 2 hPaidPC, Linux, VR, PlayStation, Xbox, Switch

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Scores are those players and critics give on the stores and sites named; each game's page says where.

More kinds of horror

  1. Psychological horror games137
  2. Survival horror games136
  3. Horror games with multiple endings115
  4. Horror puzzle games108
  5. Stealth horror games85
  6. 2D horror games59
  7. Short horror games53
  8. Co-op and multiplayer horror games49
  9. PS1 horror games41
  10. Horror escape games40
  11. Horror shooters and action horror games37
  12. Surreal horror games37
  13. Zombie games34
  14. Cosmic and Lovecraftian horror games33
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Other places to play

  1. Steam horror games1009
  2. Epic horror games97
  3. GOG horror games270
  4. itch.io horror games592
  5. PC horror games1337
  6. Mac horror games391
  7. Linux horror games261
  8. Xbox horror games367
  9. Switch horror games317
  10. Mobile horror games188
  11. VR horror games69
  12. Browser horror games236
  1. Scary games404
  2. Free horror games11
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