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Horror games about human experiments on GOG

In these games someone has been testing on people: a company lab under a mansion, a father's basement, a classified study you signed up for, a facility that keeps its captives as specimens. You are often the test subject yourself, or you walk through what the tests left behind. The fear is in the cells, the records and the people who are still running the work.

The top 26 of 26 horror games about human experiments on GOG, ranked by player and critic scores

The 26 best on GOG

  1. Outlast library art: a hulking scarred inmate with a stitched grin and glowing eyes stands in a dark asylum corridor, seen in green night vision SurvivalOutlastMurkoff's secret "research and charity" branch runs the asylum, and the store calls it hell as an experiment you can't survive. 93% on the PlayStation Store (179,484 ratings)about 5 hPaidPC, Mac, Linux, PlayStation, Xbox, Switch
  2. In Sound Mind key art: a man in a hat with a gaping mouth of teeth for a face, a cracked mannequin woman with a cat on her shoulder, a ghostly girl and a lighthouse PsychologicalIn Sound MindThe patients you find were all exposed to the same experimental chemical. 95% on Steam (7,056 reviews)10 h or morePaidPC, PlayStation, Xbox, Switch
  3. F.E.A.R. key art: the F.E.A.R. logo beside Alma, a pale dark-haired girl, on an orange background Action horrorF.E.A.R.The enemies are Replicas, telepathically controlled clone soldiers, and Perseus Mandate digs into the dark past of Armacham Technology Corporation. 94% on Steam (19,718 reviews)about 8 hPaidPC
  4. Dino Crisis key art: a scaly raptor foot with a raised curved sickle claw on a blood-smeared floor, lit against darkness SurvivalDino CrisisA scientist reported dead three years earlier has secretly resumed his Third Energy experiments on the island. 94% on the PlayStation Store (8,128 ratings)about 6.5 hPaidPC, PlayStation
  5. STASIS: BONE TOTEM key art: a frightened woman in a diving helmet underwater, a toothed orange-lit tentacle coiled around her in the green dark EscapeSTASIS: BONE TOTEMThe lab's experiments and twitching horrors are what the couple uncover as they explore. 93% on Steam (2,689 reviews)12 h or morePaidPC, Mac, PlayStation, Xbox, Switch
  6. Resident Evil (1996) key art: a pale zombie with a wound in its forehead and a bloodied shirt turns toward the viewer out of black darkness SurvivalResident Evil (1996)The store describes a biotechnical experiment gone hideously wrong behind the mansion's horrors. 94% on GOG (1,830 ratings)about 6.5 hPaidPC
  7. Resident Evil art: the dim grand hall of the mansion with carved balconies, columns, candelabras and a central staircase SurvivalResident EvilBeneath the grounds lies a secret Umbrella laboratory where experiments were carried out. 92% on Steam (37,103 reviews)11 h or morePaidPC, PlayStation, Xbox, Switch
  8. Prey key art: Morgan Yu in a red suit and glowing helmet stands beneath a huge black, smoke-like alien shape that holds the Moon and the Talos I station SurvivalPreyMorgan Yu was the key subject of an experiment meant to change humanity, run aboard the station. 91% on Steam (54,912 reviews)16 h or morePaidPC, PlayStation, Xbox
  9. Tormented Souls key art: a twisted figure stands in a red-lit corridor lined with suits of armour, glowing light behind it SurvivalTormented SoulsThe maker's bestiary says elderly patients were subjected to awful experiments and had their eyes replaced by tuning forks. 90% on Steam (8,283 reviews)12 h or morePaidPC, PlayStation, Xbox, Switch
  10. KARMA: The Dark World key art: monochrome portrait of a wet-haired young man in a padded suit with a thick collar and numbered chest plate, lit from above on black PsychologicalKARMA: The Dark WorldYou uncover hints of experiments Leviathan ran on its suspect, and possibly on Daniel, with serious cognitive consequences 91% on Steam (4,617 reviews)about 6 hPaidPC, PlayStation, Xbox
  11. I Have No Mouth, and I Must Scream key art: a man's face with a red eye and no mouth, merged into a microchip, beside the chrome title on blue circuitry PsychologicalI Have No Mouth, and I Must ScreamNimdok's chapter is set in a Nazi concentration camp where doctors conduct medical experiments 89% on Steam (4,102 reviews)about 6 hPaidPC, Mac, Linux, PlayStation, Xbox, Switch, iPhone, Android
  12. CANINE key art: a snarling dog's face seen from below, with bared white fangs and glowing amber eyes against black SurvivalCANINEAn evil corporation kidnaps pets and runs experiments on them 96% on Steam (317 reviews)about 30 minPaidPC, Mac, Switch, PlayStation, Xbox
  13. EMPTY SHELL key art: a figure in a gas mask dissolving into black ink splatters on a white, glitched background SurvivalEMPTY SHELLLogs from the 1950s lead toward the accident at the facility; The Games Machine calls it the classic experiment where everything went wrong 88% on Steam (723 reviews)about 4 hPaidPC, Switch, PlayStation, Xbox
  14. You Will Die Here Tonight key art: two grey zombies in tuxedos with glowing orange eyes in a dark mansion, above the line You will die here tonight SurvivalYou Will Die Here TonightThe creatures are described as undead experiments and manufactured nightmares lurking in the estate. 90% on Steam (601 reviews)about 4 hPaidPC
  15. Stories Untold key art: a glowing red orb among old CRT monitors, a camcorder, a keypad panel and framed photos, with GET OUT on one screen PsychologicalStories UntoldIn The Lab Conduct you follow a manual to run a series of experiments, with a camera, a drill and X-ray gear, on what looks like a human heart. 87% on Steam (5,561 reviews)about 2.5 hPaidPC, Mac, PlayStation, Xbox, Switch
  16. DYSTHANASIA key art: a tall, cracked grey creature with a spike over one eye holds the head of a limp girl in a teal gown, under the title SurvivalDYSTHANASIAIncident reports compare the creatures, called Dredges, with known past test subjects of the facility 89% on Steam (370 reviews)about 7 hPaidPC
  17. Teleglitch: Die More Edition key art: green title over a pixel-art scene of a blue robot and orange machines among a crowd of small mutants SurvivalTeleglitch: Die More EditionThe store's sinister narrative is of greedy military corporations and their covert experiments on the dead 87% on Steam (1,015 reviews)about 5 hPaidPC, Mac, Linux
  18. F.E.A.R. 2: Project Origin box art: Alma's pale face above the logo and a soldier with a rifle in a burning city, under an Xbox 360 banner Action horrorF.E.A.R. 2: Project OriginBecket learns of the Armacham Technology Corporation's secret experiments and comes to suspect he is linked to them. 85% on Steam (9,559 reviews)about 7 hPaidPC, Xbox
  19. Cold Fear key art: a blond Coast Guard sailor in a red jacket aims a laser-sighted pistol on a storm-lashed ship deck at night, under the title SurvivalCold FearA scientist, Viktor Kamsky, leads a research effort on an isolated drilling platform whose discoveries could threaten everyone. 84% on GOG (237 ratings)about 6 hPaidPC
  20. STASIS key art: a bald man in a dark segmented suit sits hunched with a hand on his head, cables trailing from his back, in a dim industrial room lit by a purple glow 2D horrorSTASISThe Groomlake turns out to be a medical frigate used for illegal research on unwilling people. 79% on Steam (1,716 reviews)about 7 hPaidPC, Mac, PlayStation, Xbox, Switch
  21. Conarium key art: a pale man's face with glowing white eyes and a light shining from his forehead PsychologicalConariumFour scientists used a strange device to push past the limits of nature; you used it, died and came back changed. 77% on Steam (2,291 reviews)about 4 hPaidPC, Mac, Linux, PlayStation, Xbox, Switch
  22. Daymare: 1994 Sandcastle key art: agent Dalila Reyes seen from behind, a glowing H.A.D.E.S. pack on her back and a gun at her shoulder, under a sky full of lightning SurvivalDaymare: 1994 SandcastleThe mission takes you into the most advanced experimental research centre in the United States, where something has gone wrong. 79% on the PlayStation Store (1,168 ratings)about 7 hPaidPC, PlayStation, Xbox, Switch
  23. Close To The Sun key art: a small steam tug on a stormy sea beneath the vast gilded art deco hull of the Helios Puzzle horrorClose To The SunThe Helios is a haven where scientists were free to push the boundaries of matter and time, and it went wrong 74% on Steam (1,359 reviews)about 5 hPaidPC, PlayStation, Xbox, Switch
  24. Darkest Dungeon II key art: four heroes, including a plague doctor and a masked man with a flintlock pistol, stand before burning houses under a flame emblem CosmicDarkest Dungeon IIThe Scholar's experiments with an eldritch force called the Iron Crown go awry and ruin the world 75% on Steam (12,147 reviews)30 h or morePaidPC, Mac, PlayStation, Xbox, Switch
  25. Security 51 key art: a moustached guard in a peaked cap at his desk beside an old computer showing a green alien, with tentacles curling in around him Night shiftSecurity 51The levels below hold laboratories, anomalies and inhumane experiments, and you test subjects for antidotes 72% on Steam (543 reviews)about 4 hPaidPC, Mac
  26. Daymare: 1998 key art: a skinless mutant with a gaping jaw lunges from a dark, blood-spattered lab corridor with biohazard and restricted-area signs SurvivalDaymare: 1998The disaster starts with the leak of an experimental biochemical weapon from a secret research lab. 69% on Steam (4,315 reviews)10 h or morePaidPC, PlayStation, Xbox

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Scores are those players and critics give on the stores and sites named; each game's page says where.

More kinds of horror

  1. Psychological horror games121
  2. Horror puzzle games109
  3. Survival horror games82
  4. Horror games with multiple endings71
  5. 2D horror games58
  6. PS1 horror games45
  7. Stealth horror games45
  8. Cosmic and Lovecraftian horror games42
  9. Mystery and detective horror games38
  10. Surreal horror games31
  11. Short horror games27
  12. Horror shooters and action horror games23
  13. Sci-fi and space horror games23
  14. Haunted house games22
Every genre

Other places to play

  1. Steam horror games1009
  2. Epic horror games97
  3. itch.io horror games592
  4. PC horror games1337
  5. Mac horror games391
  6. Linux horror games261
  7. PlayStation horror games404
  8. Xbox horror games367
  9. Switch horror games317
  10. Mobile horror games188
  11. VR horror games69
  12. Browser horror games236
  1. Scary games270
  2. Free horror games6
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