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Laboratory horror games

In these games you walk into a lab where something went wrong: a research base under a mansion, a facility on a far planet, a wrecked lab on the sea floor. Glass tanks hold specimens, notes from the staff hint at what they made, and what they made is still loose in the corridors. The fear comes from finding out what the work was.

The top 30 of 69 laboratory horror games, ranked by player and critic scores

The 30 best, 2026

  1. White Knuckle key art: the title in rough white letters with a clenched white fist on the W, over dark grey concrete PS1White KnuckleIn The Nest you pass through Infested Labs, the research sector of Habitation Blue overrun by the flora and fauna once studied there. 98% on Steam (15,667 reviews)11 h or morePaidPC
  2. Vincent: The Secret of Myers key art: two pale men at vintage microphones on a stage, one black-haired in a tuxedo, one red-haired in a red pinstripe suit holding a rose Puzzle horrorVincent: The Secret of MyersIts restricted labs hold glass tanks with a robot skeleton inside and code consoles you must work out to get through. 98% on itch.io (1,803 ratings)about 3 hPay what you wantPC, Mac, Linux
  3. Spooky's Jump Scare Mansion: HD Renovation key art: a dark mansion with lit windows under a full moon behind bare, twisted trees SurvivalSpooky's Jump Scare Mansion: HD RenovationNotes from a former researcher and corridors of broken specimen tanks tie the house to a lab where the specimens were made 96% on Steam (4,047 reviews)about 4 hPaidPC, Mac, PlayStation, Xbox, Switch, VR
  4. Misao key art: a purple-haired girl in a red top and pink skirt curled up on her side with her arms over her head among dark red splashes 2D horrorMisao - 2024 HD RemasterOne floor of the twisted school is a laboratory of specimen tanks, a brain in a jar and blood on the floor. 95% on Steam (2,588 reviews)about 2 hPaidPC
  5. Water Womb World key art: a pale grinning hooded figure with hollow eyes on a black panel over red swirling flesh, with the title on a blue bar ShortWater Womb WorldYour lab sits at the bottom of the sea, where you refill your tank and research the fish and objects you bring back. 94% on itch.io (493 ratings)about 15 minFreePC, Mac
  6. Endoparasitic key art: a blocky grey figure reaching out on a tiled floor, its body sunk into a large splash of red blood beside pure black darkness SurvivalEndoparasiticYou drag yourself through the corridors of a secret research lab to save your research. 94% on Steam (3,106 reviews)about 2.5 hPaidPC, Mac, Linux, Xbox, Switch
  7. Resident Evil 2 (1998) key art: the red Resident Evil 2 logo on black beside a pale zombie with one bulging eye and clawed fingers peering round a dark door SurvivalResident Evil 2 (1998)The way leads down to an underground research laboratory, with zombies in white lab coats 96% on GOG (2,714 ratings)about 6 hPaidPC
  8. Penumbra: Black Plague key art: a lone figure with a red backpack stands in a snowstorm between two snow-covered roofs, beside a frozen post hung with charms PsychologicalPenumbra: Black PlagueAn underground research base of a secret organisation, with labs, examination rooms and the lab of a scientist who reaches Philip over the computer network. 94% on Steam (3,007 reviews)about 8 hPaidPC, Mac, Linux
  9. Dino Crisis key art: a scaly raptor foot with a raised curved sickle claw on a blood-smeared floor, lit against darkness SurvivalDino CrisisMost of the game is spent in the labs, offices and control rooms of a military research facility. 94% on the PlayStation Store (8,128 ratings)about 6.5 hPaidPC, PlayStation
  10. Play Things key art: a doll in a red dress sits on a wooden chair under a dim spotlight on a checkerboard floor, the title in white letters below PsychologicalPlay ThingsYou run an audio test, a name call, a photo, a temperature reading and a discomfort test on each doll in an observation room behind glass. 99% on Steam (150 reviews)about 1.5 hFreePC
  11. STASIS: BONE TOTEM key art: a frightened woman in a diving helmet underwater, a toothed orange-lit tentacle coiled around her in the green dark EscapeSTASIS: BONE TOTEMBelow the rig is an underwater lab crammed with questionable experiments and biomechanical machines. 93% on Steam (2,689 reviews)12 h or morePaidPC, Mac, PlayStation, Xbox, Switch
  12. Ice Scream 8 screenshot: Boris, a clown-faced robot in a suit and tie, crawls through a dim factory hall past a small clown-faced figure in overalls, with touch controls on screen EscapeIce Scream 8: Final ChapterThe chapter opens after Lis is rescued from Rod's lab, and one generator sits in the laboratory area 92% on Google Play (81,300 ratings)about 40 minFree to playiPhone, Android
  13. Resident Evil (1996) key art: a pale zombie with a wound in its forehead and a bloodied shirt turns toward the viewer out of black darkness SurvivalResident Evil (1996)Beneath the mansion are underground lairs, including a green-lit laboratory with glass tanks. 94% on GOG (1,830 ratings)about 6.5 hPaidPC
  14. Antarctica 88 key art: a grey fanged monster roars beside the glowing cyan title on an icy blue background Multiple endingsAntarctica 88: Scary GamesScreenshots show a blood-spattered station lab where a spider-like creature crawls at you 92% on Google Play (182,456 ratings)about 1.5 hFree to playiPhone, Android, PC, Xbox, Switch
  15. Midnight Scenes: The Goodbye Note key art: a frightened eye behind the visor of a hazmat suit as a slimy green clawed hand grips it 2D horrorMidnight Scenes: The Goodbye NoteOne scene is his lab of reel-to-reel machines and control panels, where he phones home to say he'll be back soon. 92% on itch.io (378 ratings)about 30 minPaidPC
  16. Quiet is the Eyes key art: a worried researcher in glasses and a lab coat in a blue-lit office, with black splatters and a dripping handprint on the window behind her 2D horrorQuiet is the EyesYou play a researcher locked inside her own laboratory at night after it enters lockdown. 96% on Steam (225 reviews)about 15 minFreePC
  17. Caput Mortum key art: a man in a white shirt shields his eyes and holds a dagger, ringed by green serpents and winged insects before an alchemical symbol SurvivalCaput MortumLaboratories hold shelves of jarred organs, iron vats and bodies floating in green tanks. 95% on Steam (379 reviews)about 2.5 hPaidPC, PlayStation, Xbox, Switch
  18. HUMAN key art: the title in glowing, scratched white strokes over a dark, empty concrete corridor lit by a single bare ceiling bulb PsychologicalHUMANYou search an Alaskan auroral research facility for its missing employees, reading the staff's research notes on tablets. 94% on Game Jolt (627 ratings)about 30 minFreePC
  19. the white chamber key art: an anime-style girl with purple hair crouches in a red octagonal frame as dozens of pale, bloodied hands reach in 2D horrorthe white chamberThe logs of a technician named Arthur Anderson are about the station's main laboratory, the white chamber of the title. 99% on Steam (113 reviews)about 1.5 hPaidPC
  20. Endless Blue key art: a mock 1990s game case with two low-poly women back to back, one aiming a handgun, in front of the big blue title SurvivalEndless BlueThe whole demo takes place in a mysterious underwater research facility, from its dark corridors to its generator room. 94% on itch.io (316 ratings)about 45 minPay what you wantPC
  21. SCP: Fragmented Minds key art: an armoured soldier in a visored helmet before a warped red and teal void with a dropship and floating rocks SurvivalSCP: Fragmented MindsSite-113 was an anomalous research and containment facility; you search its labs, storage halls and tunnels. 91% on Steam (1,260 reviews)PaidPC
  22. Lucid Dream key art: an anime-style girl asleep in a wooden bed under a purple blanket, a small glowing-eyed creature beside her face, in blue night light AnimeLucid DreamThe dream is set in a laboratory where terrible experiments took place, as the store describes. 91% on Steam (1,027 reviews)about 45 minFreePC
  23. Resident Evil Code: Veronica X key art: Claire Redfield with an assault rifle and Chris Redfield in his S.T.A.R.S. vest raising a pistol, back to back on a dark blue background SurvivalResident Evil Code: Veronica XUmbrella's laboratories and research facilities, from Paris to the island and Antarctica, are where the horror starts 90% on the PlayStation Store (10,798 ratings)20 h or morePaidPlayStation, Xbox
  24. 10-103 key art: a green-eyed figure stands between two bodies in a blood-stained pixel-art room under an AEGIS shield emblem, red warning lights and the green title below 2D horror10-103Set in the underground Aegis Research Facility after a containment breach of an unknown entity 94% on itch.io (242 ratings)about 30 minFreeBrowser, PC
  25. Project Lunky key art: a dark red-lit creature with a long V-shaped head and outstretched arms behind the glowing red title Action horrorProject LunkyYou are unwillingly teleported into a lab where everything wants to kill you and must find the key to escape 96% on itch.io (170 ratings)about 2 hPay what you wantPC
  26. Project Looking Glass key art: a seated woman sends white wisps into a cracked mirror holding a glitching, rainbow-pixelated figure, beside the pixel title PsychologicalProject Looking GlassOne projection is a vaulted brick lab with a cart, machines and a laser warning sign. 100% on Steam (99 reviews)about 2.5 hPaidPC, Mac
  27. re:curse key art: the title in wobbly pale yellow letters with a rainbow glow on the dark red screen of an old CRT monitor Psychologicalre:curseYou play researcher Linda Langley and explore her laboratory as it distorts and degrades around her. 96% on itch.io (152 ratings)about 3 hPay what you wantPC
  28. Heaven Dust 2 key art: spiky-haired Steve with a shotgun back to back with a young woman among zombies, two helicopters in a stormy sky SurvivalHeaven Dust 2You start in a cryogenic pod in a dark lab and search labs, server rooms and secret facilities for a way out 90% on Steam (861 reviews)10 h or morePaidPC, Switch, PlayStation
  29. The Thing: Remastered key art: soldiers in hooded snow parkas charge forward under a huge snarling dog-like creature in red and orange haze Body horrorThe Thing: RemasteredA screenshot shows a lab corridor lined with glass tanks holding alien specimens. 90% on Steam (1,446 reviews)about 6 hPaidPC, PlayStation, Xbox, Switch
  30. Heaven Dust key art: a spiky-haired boy aims a handgun in front of pale zombies and a hulking mutant with an eye in its chest, beside faded top-down views of mansion rooms SurvivalHeaven DustThe mansion hid a secret research centre, with labs of old computers and tanks you search for clues. 92% on Steam (601 reviews)about 4 hPaidPC, Switch, Xbox, PlayStation

To play with friends

7 games

Short enough for one evening

Done in an hour or so

Free to play

27 games

Every game of the kind

More picks

Scores are those players and critics give on the stores and sites named; each game's page says where.

More kinds of horror

  1. Short horror games621
  2. Psychological horror games530
  3. Horror games with multiple endings417
  4. Horror puzzle games341
  5. Survival horror games259
  6. 2D horror games254
  7. PS1 horror games233
  8. Stealth horror games180
  9. Horror escape games164
  10. Surreal horror games145
  11. Horror visual novels137
  12. Anime horror games132
  13. Haunted house games131
  14. Mystery and detective horror games127
Every genre

Where you play

  1. Steam horror games1009
  2. Epic horror games97
  3. GOG horror games270
  4. itch.io horror games592
  5. PC horror games1337
  6. Mac horror games391
  7. Linux horror games261
  8. PlayStation horror games404
  9. Xbox horror games367
  10. Switch horror games317
  11. Mobile horror games188
  12. VR horror games69
  13. Browser horror games236
  1. Scary games1456
  2. Free horror games561
Every game, A to Z